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Some clinical effects of midazolam premedication in propofol-induced and isoflurane-maintained anaesthesia in dogs during ovariohysterectomy

G.F. Stegmann, L. Bester

Journal of the South African Veterinary Association; Vol 72, No 4 (2001), 214-216. doi: 10.4102/jsava.v72i4.655

Submitted: 09 July 2001
Published:  09 July 2001

Abstract

In a randomised, placebo-controlled clinical trial, anaesthesia was induced with propofol (4 mg/kg) after intravenous premedication with or without midazolam (0.1 mg/kg), in a group of 8 dogs scheduled for ovariohysterectomy. Midazolam administration induced acute behavioural changes, and increased reflex suppression after propofol induction. Compared to the control group, the dose required to obtain loss of the pedal reflex was significantly reduced by 37%, and the end-tidal isoflurane concentration during mainte-nance, reduced by 23 %.

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Author affiliations

G.F. Stegmann,
L. Bester,

Keywords

Anaesthesia; Dogs; Isoflurane; Midazolam; Premedication; Propofol

Metrics

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Total article views: 3031  

Cited-By

1. Clinical effects of midazolam or lidocaine co-induction with a propofol target-controlled infusion (TCI) in dogs
Enzo Minghella, Adam Auckburally, Patricia Pawson, Marian E Scott, Derek Flaherty
Veterinary Anaesthesia and Analgesia  vol: 43  issue: 5  first page: 472  year: 2016  
doi: 10.1111/vaa.12336

2. Fentanyl or midazolam for co-induction of anaesthesia with propofol in dogs
Gwen L Covey-Crump, Pamela J Murison
Veterinary Anaesthesia and Analgesia  vol: 35  issue: 6  first page: 463  year: 2008  
doi: 10.1111/j.1467-2995.2008.00408.x

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ISSN: 1019-9128 (print) | ISSN: 2224-9435 (online)

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